“People with an upset stomach may benefit from probiotics to being well, suggest results from animal and human study from SYNBIO TECH.”
The upset stomach, like gastric ulcers or abdominal bloating, are fairly common. The majority of people with gastric ulcers do not experience any symptoms, but some may experience pain, diarrhea, or bloating. One of the most common pathogenic bacteria is Helicobacter pylori
(H. pylori) which can lead to stomach inflammation, gastritis ulcers, and even stomach cancer if left untreated. Therefore, gastrointestinal healthcare is necessary.
The most common treatment of upset stomach infections with
H. pylori is using multiple rounds of antibiotics, but there are many side effects and the risk of bacterial resistance may be increasing. To Completely eliminate
H. pylori management strategies, effective dietaries and probiotics supplementation are gaining favor. The nutrition of balance dietaries and probiotics can maintain the good microbiota in our guts.
In addition to the research of prescription medications, studies on the mechanism between probiotic and
H. pylori have been published since 2000. The result indicated that the probiotics have a suppressing effect on
H. pylori of in vitro experiments as well as human studies (3).
The confirmed inhibitory mechanism of probiotics against
H. pylori as below (2):
- Probiotics can aggregate with H. pylori and compete the nutrition resource in stomach.
- Probiotics inhibit H. pylori growth by secreting short chain fatty acids and antibacterial substances.
- The probiotics can integrate with H. pylori and discharge through the effect of aggregation.
According to the Taiwan invention patent prospectus,
L. helveticus LA27,
L. pentosus LPS16 and
L. plantarum LP27 could successfully inhibit
H. pylori growth through the live bacteria and metabolites (1). Due to the production of antimicrobial substances competing with
H. pylori for adhesion receptors, probiotics could stimulate mucin production and stabilize the stomach mucosal barrier (4). With taking the blend formula probiotics (LA27. LP23 and LPS16) for two months, the number of
H. pylori in stomach decreased significantly in animal and human study (5).
While it cannot be viewed as an alternative to antibiotics, taking probiotics daily could still be considered as an effective complementary strategy to help manage
H. pylori infection. Total Stomach Probiotic solution - SynForU-GastroKeep - can help reduce risk of
H. pylori infections and protect the gut health.
Reference:
[1] 林金生、李幸芬、吳俊忠、鄭伯忻（2013）。中華名國發明專利號I392498。台北：經濟部智慧財產局。
[2] Goderska, K., Agudo Pena, S., & Alarcon, T. (2018). Helicobacter pylori treatment: antibiotics or probiotics. Applied microbiology and biotechnology, 102(1), 1–7.
[3] Kim MN, Lee SH, Park YS, Hwang JH, Kim JW, Jeong SH, Lee DH, Kim JS, Jung HC, Song IS. The effects of probiotics on PPI-triple therapy for Helicobacter pylori eradication. Helicobacter. 2008;13(4):261–268.
[4] Zhang, C., Zhang, H., Yu, L., & Cao, Y. (2014). Helicobacter pylori dwelling on the apical surface of gastrointestinal epithelium damages the mucosal barrier through direct contact. Helicobacter, 19(5), 330–342.
[5] Zheng, P. X., Fang, H. Y., Yang, H. B., Tien, N. Y., Wang, M. C., & Wu, J. J. (2016). Lactobacillus pentosus strain LPS16 produces lactic acid, inhibiting multidrug-resistant Helicobacter pylori. Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi, 49(2), 168–174. https://doi.org/10.1016/j.jmii.2014.04.014
Disclaimer
The information contained herein is based on data known to SYNBIO TECH by their own research and development work and is, to the best of our knowledge, reliable. This sharing of business-to-business information is intended for the general discussion between food and supplement enterprises only, and is not intended for final consumer. The information is provided at “as is” basis and its use is at the recipient’s sole discretion and risk. Information and statements herein shall not be construed as licenses to practice, or recommendations to infringe, any patents or other intellectual property rights of SYNBIO TECH or others. SYNBIO TECH hereby expressly disclaims (I) any and all liability in connection with such information, including, but not limited to, any liability relating to the accuracy, completeness, or usefulness of such information, and (II) any and all representations or warranties, express or implied, with respect to such information, or any part thereof, including all representations and warranties of title, non-infringement of copyright or patent rights of others, merchantability, fitness or suitability for any purpose, and warranties arising by law, statute, usage of trade or course of dealing. For more information, please contact: service@synbiotech.com.tw or www.synbiotech.com